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Is there a way that the signorial families of central Italy - Baglioni (Perugia), Bentivoglio (Bologna), Manfredi (Faenza) and Malatesta (Rimini) or any others - can follow the Medici and Farnese and climb to being hereditary rulers of their respective states during the Renaissance? Or were the circumstances dependent on them being related to the occupant of St. Peter's throne?
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