Funding for enforcement of prohibition was ill-defined, and was supposed to come in part from the individual states. Maryland was the extreme case, voting exactly zero over the course of the life of the 18th amendment for enforcement.
I'd guess that were that to happen in other states, we're talking about mostly the northeast, the industrial midwest, and the west coast states. On the other hand, I'd guess the Bible Belt / Old Confederacy would vote considerable funding for enforcement.
So what do we have with areas of the country with essentially a zero budget for enforcement of what is supposedly a federal law? Do we then have sizable regions where prohibition is on the books but unenforced / unenforceable, and others where it's enforced vigorously?