I'm not sure on that, but if the Spaniards could do a bit worse in Central America plus a stronger Portuguese political stability (ie: try no Iberian Union), then Portugal can be able to expand a bit further. I'm also aiming for an earlier growth of Ivangorod as early as the late 1490s into the early 1500s (Ivan III was the one who founded Ivangorod) in order to have the PoD I need to weaken England. With that kind of PoD, we might as well try to prevent Vasily III's poisoning at the hands of the boyars, leading to a saner Ivan IV. Barring that, we'll try to have a PoD that allows his mother to survive.