After Spain loses all her continental possessions, she had Cuba to consolate. The greater Antille experimented an economical boom for most the XIX Century, until the First War of Independence. It was because of the plantation system and the exportation of sugar. Then, it was the most profitable colony of Spain during most of the century.
What if Spain loses Cuba in the early XIX century along with all her American possessions? It occured to me that, in an early independent Cuba scenario it was highly probable that Spain will spill her energies towards the Philippine islands. Basically because of their weather, perfect for a plantation economy, their geostrategical value and their high profitable trade with Orient. They wouldn't have need for slaves: they have enough Filipinos to work on the sugar and tobacco plantations. Even they can transplant some spices with more modern techniques. Some Spanish immigration could be encouraged; it's not that difficult, with the opening of the Suez Channel it is possible a quicker contact with the metropoli.
At the end, which would be the consequences of a more profitable Philippines? I think Spanish influence could be more evident. Philippines could be today a Spanish speaking country as the contact with Spain would be higher than in OTL.