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Is it possible for the main early modern french kings (Charles VIII, Louis XII, or Francis I) to effectively hold their gains in Italy, especially Naples and Milan, without succumbing to their enemies?
If so, then which PoD is best for this? Charles VIII not dying early by hitting his head against a door? Francis I defeating Charles V at Pavia?
If such a victory happens, then what happens next?
Could we see an earlier rise of France as a power player in Europe?
Could this situation end up accelerating the drive towards italian unification in the long term?
Would France still have the need for an alliance with the ottomans? And, speaking of the ottomans, would Charles' weaker position favour them?
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