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Fakhr al-Din II of the Ma'an dynasty was a Druze political leader active in middle Syria during the early 17th century, notable for uniting the Maronite and Druze groups of modern Lebanon in a military effort against the Ottoman administration of Syria. At a time, he apparently held sway over lands stretching from northern Palestine to Palmyra, until his downfall at the hands of Sultan Murad IV in 1635. Before that, he pleaded to numerous European courts (such as Tuscany) for assistance.
How could Fakhr succeed in his objective of freeing most of the Levant from Ottoman rule? Perhaps through the Spanish and their Italian fiefs/allies not being too embroiled in the Thirty Years' War after the 1620's? Would they be any interested in allying with him? What about Safavid Persia?
Would a successful Mount Lebanon state severe connections between Ottoman Anatolia and Egypt, flaring up tensions in the latter province?