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In 1660 Mary, Princess of Orange, mother of William III, Prince of Orange (future King of England), died of smallpox. William obviously didn't die and became a central figure in European politics.

However what if William had been with his mother in London where she contracted the illness, or he contracts it in the Netherlands at around the same time. This leaves the next person in line to be either William III's aunt, Countess Louise Henriette of Nassau - also married to the Duke of Prussia, - or the nearest male candidate is William's cousin Henry Casimir, son of Albertine Agnes and who's only 3 years old.

My question is, how would the succession go? The wars in the east are over by this point, so could the Prussian Duke try and help install his wife as the Princess of Orange, and would the Dutch accept her? Or would they rather go for a male candidate, despite his age?

If they go for Henry Casimir, would Louise Henriette try and force her claim, or would she merely accept the decision. If she doesn't who would the Dutch themselves support, would we see a civil war, or would it be more of a Prussian invasion of the Netherlands?
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