Let's say that Colombus doesn't go exploring West in 1492, and the Americas are not rediscovered by Western Europe. This doesn't stop the colonization revolution because Portuguese and the Dutch had already been exploring the Indian Ocean and had been going past the southernmost part of Africa. Hypothetically Sub-Saharran Africa and the Indian Ocean Basin takes the place of the Americas as the big target for colonization and migration.With Western powers having to extend much farther to colonize territories with people who aren't affected by European disease requiring more resources to quelling native populations. With West Europe spending more men, time, and resources on Africa. With this focus on the more difficult to tame colonies, West Europe will divert far less attention towards lands directly to its east in the short term. This could stimulate a situation where Italy, Russia, the German states and the Ottoman Empire become more powerful. Italy due to its geographic location is the most likely to rise up and become a great power. It would attempt to expand and control the central portion of the Mediterranean basin, expanding as far west as the Balearics, and would attempt to expand east to control Dalmatia, Corfu, Peloponnese, Crete, and Cyprus, and would move south to Libya and Tunisia. Russia would not be greatly affected and expand in the same manner as it did it the OT. The German states were unified by Napoleon's France and later Prussia. Without an American Revolution France would not Erupt into war. Perhaps a similar Revolution could erupt in a new African state triggering France's revolution, but that is up for discussion. Eventually Europe would attempt to break the Ottoman Empire's hold on the the thin strip of land that would eventually become the Suez Canal would become a focus of the European powers. Whoever dominates that territory would come to hold a great amount of power. Which power does that is also up for discussion. What is up for discussion is how Africa and the Indian Basin would be divided up, what kind of independence revolutions would happen, and what the international system would be like.