alternatehistory.com

Here is another challenge, come up with a scenario that dooms European America, ie. all European colonies in America ultimately fail.

Mine is that one of the Italian city states says yes to Christopher Columbus instead of Spain, thus the Italian mercantile companies run New World exploration and trade entirely, there is quicker profit in it if the Americas does not have the regulations brought on by colonialism, so they strangle all colonies (similar to what happened to Quebec when it was founded) this pattern continues with the rest of the European countries.
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