The Narváez expedition was a Spanish expedition started in 1527 with the object of establishing colonial settlements and garrisons in Florida.
The crew initially numbered about 600, including men from Spain, Portugal, Greece, and Italy. Landing near Sarasota Bay, the expedition was split, with 300 men sent north overland in search of gold. When the supply ship failed to appear at the rendezvous, the group attempted to transit to Mexico by overland march & then raft. Four survivors of the 300 reached Spanish settlements in Mexico a few years later. Survivor Cabeza de Vaca left a written text about the expedition in his La Relación (The Relation), published in 1542 as the first written account of North America. With later additions, it was published under the title, Naufragios
So Wi the northern group had sat tight at its redevous, near modern day Pensacola, been resupplied & settled in building a fort & permanent station there or a little further west. Does this bring Spanish settlement to this portion of the Gulf coast & eventual penetration up the Mississippi in the later 16th Century? That is can the French control be preempted?