First, yes there was (and had been since the Revolution) talk/discussion in Virginia about ending slavery. Unlike the deep south, and even North Carolina, the early "revolution era" southern anti-slavery cause didn't die in the early 1800s in VA *and yes economics were a major issue). At the time of Nat Turner (AUG 1830) there had been appears to have been a consesus (all the major VA political leader) around the idea of a gradual (10-15 year) end to slavery with based on resettelment and some form of compension to owners.
Nat Turner's actions ended in any chance.
So if, no Nat Turner, and Virginia goes through with ending slavery by 1850... No re-sale futher south, resettlement for most, and let's say, tax breaks (most likely something like what we call tax credits today), like future;
1. Virginia most likely becomes the center of gravity for the "main-stream"
abolitionist movement. The movement becomes more akin to the 1770-90s abolitionists, based on the economic failures of slavery and to a lesser degree the Consititional/ Human Rights (not a term they would use) issue. BIG TAKE AWAY, the radcial abolitionst are marginalized even more, very possible there's no money support.
2. Virgina style abolition in MARYLAND and DELAWARE, I would expect it to be quicker to match VA's 1845 date.
3. At least in KENTUCKY, TENN and NORTH CAROLINA, a serious abolition movement, on VA's terms is reborn. By the late 40's they are one pole of the debate.
4. The other pole is SOUTH CAROLINA (and the rest of the deep South as supporting players). The battle instead of being us versus that minority of "radical" abolitionist, it's between the hard-liners (same as our OTL) and moderates who will start to look as the "Virginia Solution" and at least want to discuss it.
Couple of wild cards;
a. Missouri and new states, no sure how that goes, if VA, TN, NC, and KT end slavery Missouri will have to face the issue. And it slavery is receeding I don't see the Federal government (i.e. the majority of states now non-slave) aggreeing to new Slavery states, so it you may see statehood go slower.
b. Secesssion... I believe if the hardliners in the deep south win /hold the line, secession may could earlier, First the question of an anti-slavery President is going to could up earlier. Second see Wildcard (b), maybe FL, TEXAS, or CA become the tripwires.