Natalie portman would be interesting, too...she did eventually do a similar psychological horror-type movie in the black swan years later, so she can pull it off...The problem is that she might be more well known due to star wars, so she might be expensive...And, since clock tower most likely won't have a big budget due to being a niche game and an uknown property, we might go with hathaway, instead. She is still relatively well known due to princess diary, but She didn't have a reputation yet, so she'll be cheaper.