Maria Francisca of Nemours has more children

So, this is something I've been considering recently. Otl Maria Francisca of Nemours, married Pedro II of Portugal in 1668 and gave birth to a daughter in 1669, but after that had no more children. When she died in 1683, Pedro remarried and had a fair brood of children, so, my question is this, what changes if Maria Francisca is able to have more children after 1669, and this includes a son and another daughter?
 
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