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With a PoD of no earlier than 1500 (to give a round cut-off date), make all Capetian houses (that is all Houses going back in the male line to the Capetian main line), most prominently among them Valois and Bourbon, extinct in the male line until no later than 1800.

When would this best happen? I mean, with a 300 year span one could just say "Butterflies, eventually", but, yeah, what would be an "efficient" PoD? And what would be the consequences?
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