(Hopefully no necro, given it is a timeline)
I had a thought today. Had the Simpsons been cancelled, it still would have continued in the Bongo comic series, and I think probably would have been very strong in comic sales, at least in the initial years after it's cancellation. A comic book doesn't have to pay actors or recording fees or animators, so oddly that may be how many younger people know the Simpsons compared to knowing them from a television program (which would certainly continue in syndication). Certainly the Sonic the Hedgehog comic, based on the 90s animated series, is a big seller for Archie comics still today, long after the animated series was cancelled. I also think that the comic series Simpsons writing is much better than what is on the show today.
You also open up the prospect of spinoffs, as again, there is no special cost to comic books that weighs the industry down as being as expensive as television or film. There's already a Bart Simpson comic, and you could easily have spinoffs based on any number of things. Perhaps an anthology series of the tales of Springfield of multiple characters, or Troy McLure, or Krusty the Clown, and the list goes on.