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Are there any situations in European history where someone who was born so far down the line of succession that they never expected to have any chance of inheriting and then ending up with the throne?

Queen Victoria of Britain was 5th in line for the throne but even as a baby there was viewed as a good chance she would eventually be queen. Queen Elizabeth I was third, but still in the mix.

Louis XVIII was 4th at the time of birth.

Any suggestions for more and farther down?
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