King James V of Scotland weds Frances

King James V of Scotland married Madeleine of Valois. He married Mary of Guise.
Suppose King James marries his first cousin, Lady Frances Brandon, the daughter of Charles Brandon, Duke of Suffolk and Mary, the sister of James V's mother, Margaret Tudor.
What happens then?
 
Well, no more Auld Alliance, no Rough Wooing (unless Henry VIII wants the Tudors to be a load of inbred rednecks) no Anglo-Scottish wars generally. Edward VI tries to make Frances' niece Margaret Queen upon his death, but Bloody Mary and the Scots both get involved - probably a two- or even three- or four-way civil war in the 1550s. Then Mary and Elizabeth do roughly the same sort of thing and are succeeded by the Scottish monarch (presuming Mary wins as OTL - she would have executed Lady Margaret Clifford, no sweat, leaving the Scots as the only heirs in the late 16th century) and then Union, but with different people on the throne - and if James V has a son, then the Lennoxes will be a threat to the main line.
 
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