Some years ago, when I was still a lurker on here, I was interested in this idea, but my conclusion at the time was that this would be unlikely because African Wild Dogs were likely to consider humans as competitors due to their hunting habits, but recent advances in the study of the history of the domestic dog are suggesting that humans and dogs may have developed cooperative relationships based on domestic dogs being closer-related to an ecomorph of wolves that was specialized for hunting megafauna that is so-called the "megafaunal wolf". That being said, combined with the knowledge that certain packs of African Wild Dogs are known to specialize in hunting zebras and water buffalo, and that it is possible that humans co-evolved with a ghost lineage of wolves that in a sense herded Pleistocene megafauna, would it be feasible for humans in Africa during the Pleistocene, when the Sahara was as dry if not even drier than it is today, to have developed such a cooperative relationship with these dogs?
Interestingly enough, recent research is starting to suggest that there may have been multiple domestication events, which is very interesting for the genre of alternate history as it opens new doors in terms of PODs involving animal domestication. A timeline that involved the domestication of Lycaon pictus would not necessarily exclude the domestication of Canis lupus, and if our relationship with this ghost lineage of dogs was one of observation and possibly cooperation in hunting, then, if dogs are not domesticated before the arrival of humans in the Americas, one might presuppose a similar relationship might develop between humans and dire wolves, which were also specialized hunters of megafauna that humans might observe and possibly cooperate with if they were not already cooperating with another invading species. So, one could be looking at a world in which African Wild Dogs and regular domestic dogs are in competition with one another for the cooperative relationship with humanity, with African Wild Dogs possibly being widespread as domesticates in Africa, particularly Sub-Saharan Africa, while regular domestic dogs are dominant elsewhere.