Invocation of the 25th Amendment

Any of the murder attempts or plans against Presidents could have left the inbumbent unconious for a significant period of time
 
JFK comes to mind but was it in place back then? Bush Jr got a granade tossed at him in Georgia, that would do.
 
No, the 25th was ratified in 1967 IOTL. Though if JFK hadn't hired Hans Kraus, he might've ended up like FDR in a wheelchair. IOTL there was a reason why he never boarded or exited the helo from the South Lawn...
 
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