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This scenario I think is borderline ASB, but not quite impossible either. In 2006 Mexican president Felipe Calderon declared war on the drug cartels, which has been going on since then, and the war becoming extremely brutal.

What if the cartels took the government's declaration of war super seriously, put aside their differences, organized and by pulling all the strings of corruption they can get ahold, manpower and weapons, they manage to build up enough power to stage a coup in 2010 to overthrow the president that declared war on the cartels, and establishing a cartel-run junta making Mexico a drug cartel run country?

How would this impact history and how would the USA react?

If this is too ABSish I will move it there, but I think that situation is possible, just really, really hard to pull off.
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