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As it says on the tin, we all know the Spanish empire was too big to colonize with much of northern Mexico uninhabited along so what is the impact of a Spanish empire that stays small putting most of there effort into dominating the Carribean and its adjacent areas.
What becomes of the Inca if Spain does not colonize western South America.
Likewise, what happens to the pueblo indians long term and the other lands of northwestern and greater mexico without spanish colonies.
Finally what impact is this likely to have outside of the new world.