There could be a way. In OTL, Henry II had granted Admiral Nicolas de Villegagnon the right to establish a Protestant colony in the New World in 1555. The chosen location was in southern Brazil, but for various reasons the attempt failed.
Now, Jacques Cartier had claimed what would become Lower Canada on behalf of the French Crown in 1534, and the latter began looking for ways to send settlers to the colony from 1540. The POD could be that Villegagnon is sent to settle New France rather than Brazil. If the colony holds, it could become a place of refuge for the Huguenots during the Wars of Religion, a development facilitated by the fact that La Rochelle, one of the main French ports on the Atlantic, was a Protestant stronghold.