alternatehistory.com

So i watched a video from Monsieur Z. In the video WW1 didnt happen and therefore the US stayed isolationist.
In his scenario the US gained the unpopulated States of Canada, Cuba and northern Columbia because they didnt had any land left in the US to take away from the natives.
(The difference in his timeline is that Wilhelm II is killed in 1901 and his Wilhelm III is the new and better Kaiser)
So my Question is woud the US keep "manifesting Destiny" after there done with it in the US and if yes what land woud they want to have ?
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