All I'm going to do here is to chime in with a reminder that English and British history are chock full with fascinating accidents having to do with how many and which children of which monarchs and their close family survive, and which do not. Of course the all-time best example of this remains Queen Anne. But by my money, a runner-up is the children of Charles Brandon. He had eight legitimate, or legitimized, children. The two daughters born to Anne Brown, the two sons born to Mary Tudor, the two daughters born to Mary Tudor, and the two sons born to Catherine Willoughby. Every daughter makes it to adulthood. Average age at death of a son capable of transmitting the dukedom of Suffolk, fifteen years. Average age at death of a son with a potential claim to the throne of England, eight or nine years.
Now, it's not like I want to make the absolutely irresponsible claim that a Tudor might be capable of harm to a nephew, a cousin, or a cousin once-removed, when matters of the succession are involved. (What kind of Tudor would it be, we might ask, who would put the succession before family?), but someone with a less than completely charitable view of the king might think the early deaths of the sons by Mary some evidence of what he actually thought about the sons of Charles Brandon succeeding him. Or perhaps, someone at his court who gets regularly compared in the historical literature to Lavrenti Beria. And I'm not venturing to say anything about the deaths of the sons by Willoughby, that's supposedly a straightforward fever.
Remember, by the way, just how recently the Brandon family had risen. And how unusual their ascent to the English throne would be, even in comparison to the Tudors.
And on an unrelated note, I did actually encounter online once a person who said there was no evidence someone as morally conservative as Henry would ever actually engage in extramarital sex, and that that whole business with Anne Stafford was unproven anyway, and how dare we cast aspersions on someone who clearly believed in the institution of marriage as much as England's great King Harry? It was all I could do to restrain myself from the obvious profanity when I asked where she thought the Duke of Richmond came from.