Too remanicent of our time line.Everybody on earth become mentally ill.
That's not hard that's impossable.With a POD of 65 Milllion BC, make Justin Bieber a good musician
Not meant to be taken seriously
If native people had better teghnology, in even a few areas they could have defeated Columbus. Suppose they had guns like those in use in Wprld War One? Columbuses men set up a aqubus and shoot it to scar the natives. They run alright. They home and get Springfield or Anfield type weapons. Columbus and his men are soon wiped out.Make Mormonism the largest religion on the planet.
OR
Create a unified state over both america's before Columbus arrives and have them launch a successful invasion of Europe after crushing Columbus's fleet.