Your challenge, should you choose to accept it, is to make this not blasphemous.
In other words, have "Holy Fuck" or some reasonable synonym be an acceptable Christian usage, e.g. for naming churches, or something. Along the lines of "Agia Sophia" = holy wisdom, "Sainte Foy/Santa Fe" = holy faith, "Familia Sagrada" = Sacred Family.
Yes, it would almost certainly require the removal of e.g. St.Augustine of Hippo amoung others, and have the Church have a much more open view of sexuality.
It might very well require that the 'Virgin Birth' be considered heretical.