That is already the case in South Africa with regards to South Asians. Although South Asians only make up about 2% of SA's population (about 10% in KwaZulu-Natal province), they are, after whites, the richest population group, and are influential in the life of the country, especially politics, and cricket.
Imtiaz Patel - CEO of Supersport
Kass Naidoo - general manager Cricket SA
Essop Pahad - Minister in the Office of the Presidency
Aziz Pahad - Deputy Foreign Minister (and Essop's brother)
The late Krish Mackerduj - former head of SA Cricket and former ambassador to Japan
Kader Asmal - former Minister of Water Affairs and something of an elder statesman in the SA politics
Valli Moosa - former Minister of Environmental Affairs and Tourism and now on Eskom's (state-owned electricity utility) board
Jay Naidoo - former cabinet minister and successful businessman
I don't think you'd see a South Asian majority state, but I think South Asians would possibly be analagous to the Jews, a small but influential, prosperous minority.
Having no apartheid in South Africa would result in a larger Asian population in SA, and by extension Southern Africa.