Make a USA with states in South America and the Caribbean but no land west of the Mississippi. POD post-1774.
Make a Brazil with colonial holdings including something in West Africa and Baja California and possibly Sinaloa (but no other Mexican land), but no connection to Portuguese crown. POD post-1750.
Make Italy have a port on the Atlantic (in Europe, not a colony or anything). POD post-1900.
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Make Western culture have a fundamentally different perception and ideal of love...
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Nah, do the Brazil one. That'd be wicked cool.