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The POD for this is in 1976. Reagan's primary challenge against President Ford is successful with the possible Pod being that Reagan does not name Schweiker as his running mate until after he secures the nomination. Carter, despite running a flawed campaign in the general election, defeats Reagan by an even bigger margin than he beat Ford IOTL due to Reagan's more extreme/hawkish views. The results look something like this (all the states that went for Ford by less than 3% OTL are flipped to Carter):
Fmr. Governor Jimmy Carter (D-GA)/Sen. Walter Mondale (D-MN): 52.6& PV 378 EV
Fmr. Governor Ronald Reagan (R-CA)/ Sen. Richard Schweiker (R-PA): 45.5 PV 160 EV