Afghanistan, Iraq, and Pakistan have literally the most corrupt govts on the planet. It wouldn't surprise me to see that becoming an issue in the buildup, or see someone trying to tie that to Obama and/or Repubs, no matter how true it were or not.
The Akaka Bill (Native Hawaiian recognition) may come up next year or 2011 and I'd expect a lot the same kind of bluster about "Obama's ties to radicals." Obama vowed to sign the bill, which has the support of everyone from moderates of both parties in Hawaii to a few secessionists. We may see a few birthers going on about this bill as supposed payoff for covering up "the secret about his birth."