Ok, this is really broad, so feel free to interpret the question more or less however you'd like. The only restriction I'd like to posit is no serious tech uplifting (so no 'industrial Rome' type scenario).
Many discuss the trade between the Roman world (the Mediterranean and Europe) and those civilizations to their east in terms of Roman specie flowing eastward in exchange for eastern trade goods - spices, silk, etc. That is an oversimplification, and the Romans did have trade goods of their own that those in the east valued. I also think the concern over specie leaving the empire is overstated by those that didn't understand economics as well as we do. But lets just accept the basic framework.
What trade goods could Rome conceivably have that they did not, historically? Ideally, these would be trade goods that were not available in the East, but that is not a requirement. These could be cultivating new crops or species that they could have had access to, but did not (even crops from the east), or manufactures that were appropriate to their level of technology. Consider trade goods from West Africa, Northern Europe, etc.
Many discuss the trade between the Roman world (the Mediterranean and Europe) and those civilizations to their east in terms of Roman specie flowing eastward in exchange for eastern trade goods - spices, silk, etc. That is an oversimplification, and the Romans did have trade goods of their own that those in the east valued. I also think the concern over specie leaving the empire is overstated by those that didn't understand economics as well as we do. But lets just accept the basic framework.
What trade goods could Rome conceivably have that they did not, historically? Ideally, these would be trade goods that were not available in the East, but that is not a requirement. These could be cultivating new crops or species that they could have had access to, but did not (even crops from the east), or manufactures that were appropriate to their level of technology. Consider trade goods from West Africa, Northern Europe, etc.