Elizabeth Dole's record and resume is pretty amazing, even prior to her being a Senator.
-Worked in the Johnson White House
-Supporter of the Women's Liberation Movement in the 1970s and Equal Rights Amendment
-Commissioner of the Federal Trade Commission (1973-1979)
-Director of the Office of Public Liaison (1981-1983)
-Secretary of Transportation (1983-1987)
-Secretary of Labor (1989-1991)
-President of the American Red Cross (1991-1999)
Dole was also the first woman to ever head a branch of the military, as the Coast Guard was under the jurisdiction of the Department of Transportation when she was Secretary.
Covering just about every area of domestic policy, the only thing Dole really lacks is Foreign Policy chops. Jeanne Kirkpatrick works given how she was UN Ambassador, on the National Security Council, the Foreign Intelligence Advisory Board, Defense Policy Review Board, and chaired the Secretary of Defense Commission on Fail Safe and Risk Reduction of the Nuclear Command and Control System,
They're also somewhat bipartisan considering how they both were Democrats who became Republicans.
What if Elizabeth Dole and Jeanne Kirkpatrick had been the 1996 Republican ticket?