Of course the American indigenous population was decimated by diseases that had no experience with. It happened to the Faroe islanders when they were exposed to measles. It even happened to rural Americans when exposed to diseases like measles for the first time in civil war camps. When plague returned to Europe in 1361 it targeted those born after the initial plague wave. It has nothing to do with genetics. Any inexperienced population or section of a population without previous exposure will suffer disproportionately when exposed to a new disease. Any time and any where.
Yeah, that is unfortunately true. While you can inherit good immunity, it will only ever be for illnesses that your native population/group has past experience with. A totally new illness will be far more dangerous, given the complete lack of immunity in the history of the population.
I remember I once had a minor allergic reaction to a wasp's sting, but never afterward on the rare occassion a wasp stung me again. You just need to develop immunity towards certain diseases or natural biochemistry based injuries. An individual's body needs some prior experience.
Another possible way is for the Viking expositions to survive and spread their genes and immunities through the Tribes.
I have severe doubts about that. The Scandinavians didn't mingle with the natives in OTL due to there being little need for that. There's a reason the few confirmed settlements were only part time and stuck to the coast. All the fantasies about OTL Scandinavians venturing deep into North America and planning colonisation en masse are rather silly.
I've seen some timelines try to come up with compelling reasons for why Scandinavians would use the North American coastline for more than just seasonal resource gathering, with appropriate seasonal accomodation. Some good timelines, some highly iffy timelines. That's the key issue there. Enough people coming over, founding sedentary communities. Iceland was easy-peasy, "no one here but us birds and polar foxes". Greenland detto, the Greenlandic Inuit branch of the Thule culture apparently arrived there even later than the Scandinavians, which is amusing. So Iceland and Greenland and the aforementioned Faroe Islands make a lot of sense for colonisation, harsh weather and harsh nature aside. No natives to squabble and deal with. One of the older Vinland-based timelines, Empty America, had no native cultures in America, so the Scandis staying was a no-brainer (though that TL does have issues, being from the older days of the fandom). Others had groups of Norse and other settlers banished for good, and they decided to settle over there because they ran out of other good options. The idea of "Vikings" colonising North America for the lulz, and the same with the Chinese under Zheng He's leadership, is anachronistic. It ascribes them views and goals that were more typical of early modern Europe, during the "Age of Discovery", whereas the goals of these two groups were a little different. Even accounting for Scandinavian colonisation of the North Atlantic, they wanted to play it safe with that one, and only settle a land that wouldn't be a nightmare to defend from local natives or outside raiders.
There's also the issues of having unfortunate misunderstandings with the natives, which prevented any sort of allying for the sake of trade, let alone buddying up and intermarrying. The misunderstanding apparently included giving the natives cheese as a gift and sign of good will, and the annoyed natives then returning with a vengeance, after some of them received food poisoning due to lacktose intolerance (which nobody could have known about at the time).
Maybe intermarrying and extended contact between Scandinavians and Native Americans would help the latter in the long run when it comes to diseases, maybe not. There are too many if-s and preconditions necessary to make that sort of highly optimistic leap.
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