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Something I've seen a thread on twice now is the idea of Edward of Westminster, Prince of Wales, marrying Isabel I, Queen of Castile. Would this have been possible? Or even plausible? And what might the effects of said match be on the world? No Catholic monarchs, for one (the idea of Fernando V marrying Marie of Burgundy or even La Beltraneja makes for some interesting speculation). Could it even tip the scales in the house of Lancaster's favor? Or would the Yorks be too entrenched by the time EoW could do anything about it, assuming an alt-1470/71 campaign?