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The Hamilton-Burr duel in Weehawken in 1804 gave rise to an anti-dueling movement. As early as September 1804 Timothy Dwight preached his famous sermon against dueling to the students of Yale. https://books.google.com/books?id=cx9dAAAAcAAJ&pg=PA3 Even in the South laws were passed (some had been passed before the Weehawken duel) not only making dueling a crime (which it already was under the common law) but barring duelists from public office and the professions (obviously, enforcing these provisions was another matter...):

"The earliest laws sought to cut the tie between dueling and honor by banning duelists from the mark of public favor--public office. [FN164] It was an old idea; both Massachusetts and Connecticut had disqualified duelists from holding political office since before the Revolution. [FN165] In the South, such provisions became common in the years around 1800. In 1799, Kentucky banned duelists from holding public office, [FN166] followed by North Carolina in 1802, [FN167] Tennessee in 1809, [FN168] and Virginia in 1810. [FN169] Two years later South Carolina enacted a similar law which not only barred duelists and their seconds from holding public office, but banned them from practicing law, medicine, 'or any other trade or calling whatsoever.' [FN170] Similar laws soon appeared on the books in Illinois (1815), [FN171] Georgia (1816), [FN172] Alabama (1819), FN173] and eventually Mississippi (1822), [FN174] and the District of Columbia. [FN175] Mississippi [FN176] and Kentucky [FN177] were among the states that also placed prohibitions in their state constitutions allowing duelists to be barred from public office." http://www.gfactorconsulting.com/Downloads/Dueling/Wells.pdf

Suppose that after the Hamilton-Burr duel the US Constitution was amended to make ineligible for the presidency any person who had participated in a duel. This presumably eliminates the presidency of Andrew Jackson. (This is true even if it is limited to duels fought after the ratification of the amendment--Jackson is hardly likely to restrain himself for the sake of what in the 1800's and 1810's must seem a very unlikely future presidential candidacy.) Maybe Henry Clay is also barred--will the thought of disqualification from the White House really prevent him from dueling with Humphrey Marshall in 1810?

Any other effects? (Abraham Lincoln *almost* got into a duel with James Shields but it was called off at the last minute.)
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