So in the "Mesoamerican Janissary" thread I posited a scenario that may allow for European and Mesoamerican civilizations to stay on a more equal standing (note that a completely equal technological standing is impossible without a prehistoric POD). This scenario was that trans-Atlantic contact was initiated not long before the Black Plague ripped across Europe. This would be interesting, because while Europe is losing so much of its population, so would the Native American states and cultures. What would following interactions look like?