Diego I of Spain and Portugal (b.1575: d.1641) m. Gregoria Maximiliana of Austria (b.1581: d.1640) (a)
1a) Joanna of Spain (b.1598: d.1669) m. Louis XIII of France (b.1601: d.1643) (a)
1a) Anne Louise de Bourbon (b.1621: d.1640)
2a) Louis XIV of France (b.1623: d.1704) m. Mariana of Austria (b.1634: d.1696) (a), Maria Anna Antonia of Austria (b.1672: d.1731) (b)
1a) Miscarriage (b.1656)
2a) Christine de Bourbon (b.1660: d.1671)
3b) Louis XV of France (b.1699)
4b) Miscarriage (c.1700)
3a) Philippe de Bourbon, Duke of Angouleme (b.1625) m. Marie d'Orléans-Longueville (b.1625: d.1707) (a)
1a) Marie Anne de Angouleme (b.1649)
2a) Francois Jacques, Duke of Angouleme (b.1652)
3a) Miscarriage (c.1655)
4a) Marie Jeanne de Bourbon (b.1627: d.1659) m. Charles Emmanuel II, Duke of Savoy (b.1634: d.1675) (a)
1a) Miscarriage (c.1655)
2a) Stillborn Boy (c.1657)
3a) Stillborn Boy (c.1658)
4a) Stillborn Boy (c.1659)
5a) Henri Gaston de Bourbon, Duke of Anjou (b.1630: d.1660) m. Henriette Adelaide of Savoy (b.1636: d.1676) (a)
1a) Eleanor de Anjou (b.1655)
2a) Charles, Duke of Anjou (b.1658)
3a) Marie Adelaide de Anjou (b.1659)
2a) Ferdinand of Spain, Prince of Asturias and Portugal (b.1602: d.1603)
3a) Maria Eugenia of Spain (b.1603) m. Charles I of England (b.1600: d.1649)
1a) Charles II of England (b.1624) m. Louise Henriette of Nassau (b.1627: d.1667) (a)
1a) Henry IX of England (b.1648)
2a) James Stuart, Duke of York (b.1651: d.1666)
3a) Margaret Stuart (b.1657: d.1665)
2a) James Philip Stuart, Duke of York (b.1627: d.1649)
3a) Frederick George Stuart, Duke of Clarence (b.1628: d.1667) m. Marie Marguerite of Lorraine (b.1629: d.1679) (a)
1a) Miscarriage (c.1659)
2a) Margaret of Clarence (b.1666: d.1666)
4a) Catherine Stuart (b.1630)
5a) Henry Augustus, Duke of Gloucester (b.1635) m. Margaret Yolande of Savoy (b.1635: d.1669) (a)
1a) Mary Christina of Gloucester (b.1656)
2a) William Edgar of Gloucester (b.1659)
3a) Anne Louisa of Gloucester (b.1661)
4a) Isabella Eleanor of Gloucester (b.1663)
5a) Arthur Philip of Gloucester (b.1666)
6a) Elizabeth Stuart (b.1638: d.1661) m. William II, Prince of Orange (b.1626: d.1659) (a)
1a) Marie Henriette of Nassau (b.1658)
2a) William III, Prince of Orange (b.1660)
7a) Anne Stuart (b.1640: d.1660) m. Louis XIV of France (b.1638) (a)
1a) Marie Francoise de Bourbon, Fille de France (b.1657)
2a) Louise Christine de Bourbon (b.1659)
3a) Margaret Therese de Bourbon (b.1660)
4a) Miscarriage (c.1606)
5a) Diego II of Spain and Portugal (b.1610) m. Henrietta Maria of France (b.1609) (a)
1a) Philip, Prince of Asturias and Portugal (b.1630) Eleonora Gonzaga (b.1630: d.1686) (a)
1a) Maria Christina of Spain (b.1656)
2a) Eleanora Clara of Spain (b.1657)
3a) Charles of Spain (b.1660)
2a) Charles of Spain (b.1633: d.1634)
3a) Miscarriage (c.1634)
4a) Michelle Eugenia of Spain (b.1640) m. Ferdinand IV, Holy Roman Emperor (b.1633) (a)
1a) Ferdinand of Austria (b.1655)
2a) Stillborn Boy (c.1656)
3a) Stillborn Boy (c.1657)
4a) Maria of Austria (b.1658: d.1660)
5a) Stillborn Boy (c.1660)
6a) Stillborn Boy (c.1661)
7a) Stillborn Girl (c.1663)
8a) Charles of Austria (b.1664)
9a) Stillborn Boy (c.1665)
10a) Catherine of Austria (b.1666)
11a) Stillborn Boy (c.1669)
12a) Stillborn Boy (c.1669)
13a) Stillborn Girl (c.1672)
6a) Miscarriage (c.1611)
7a) Isabella of Spain (b.1614: d.1630)
8a) Michelle Christina of Spain (b.1616: d.1630)