As most football fans know, the San Diego Chargers had the #1 draft pick in 2004 and wanted to select Eli Manning. Manning refused to play for San Diego (the reasons are unclear, but one of the thoughts was that he didn't like how they treated QBs, like Drew Brees and Ryan Leaf) and, of course, the Chargers decided to draft Larry Fitzgerald instead. The Brees-Fitzgerald combo would ultimately lead to the Chargers winning Super Bowl XLI against the Saints and getting to the AFC title game in 2008, losing to the then-undefeated New England Patriots and to the Chargers becoming a solid playoff team for years (winning three AFC titles and two Super Bowls); it's not for nothing that Pacific Marine Stadium has been called "the house Drew and Larry built."
Eli Manning didn't turn out too badly, becoming a solid quarterback for the Cardinals and winning a Super Bowl against the Steelers in Super Bowl XLV, which has been considered to be one of the best Super Bowls of all time. Ben Roethlisberger was another beneficiary; drafted by the Giants, he helped them beat the Patriots twice and won four Super Bowls (though many would argue that they came with the famous Giants defenses that included Richard Sherman, Cam Chancellor, et. al.; it's not for nothing that people compared them to the 1980s Giants defenses with Lawrence Taylor and Carl Banks)...
So, WI the Chargers did draft Eli Manning (A.J. Smith said that he strongly considered doing so, but was convinced to draft Larry Fitzgerald to ensure a solid wide receiver for Drew Brees)? Manning has stated that, if drafted by the Chargers, he would have sat out the 2004 season, so who would the Chargers trade him to and for how much? Maybe he gets traded to New Orleans (it would make sense; his father, Archie, played for the Saints) and, if so, this certainly butterflies away their selection of Aaron Rodgers...
(OOC: Pacific Marine Stadium is located in National City, on the site of an OTL stadium proposal; assume butterflies ensure it gets built ITTL...)