Could Argentina be broken up after the independence?

Argentina was always known for it's regional differences, like Brazil or even Germany. During the earlier years of Argentina there was a conflict between the confederationists who wanted a very decentralized country and the unitarists who wanted the power based on Buenos Aires. I was wondering if this couldn't be overblown and break up Argentina, with provinces like Cordoba breaking off and forming their own small republics. Is that possible?
 
It kinda happened OTL; Uruguay was part of La Plata, and was originally the core of the Federal League. It then got briefly annexed by Brazil before being made independent as a compromise after an Argentine-Brazilian war. It might be plausible to have a bigger alt-Uruguay emerge that contains all six provinces of the Federal League (Cordoba, Misiones, Corrientes, Entre Rios, Santa Fe, and what would become Uruguay).
 
Besides OTL’s breakaway of Paraguay and Uruguay, i could also see a split producing a Republic of Buenos Aires, with a border extending to Neuquen and with claims to Patagonia, and a federalist inheritor of the Congress of Tucumán comprised of the remaining northern provinces.
 
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