From the time of the Assyrian conquest to the Ptolemaic dynasty, Egypt had struggled repeatedly and ultimately unsuccessfully to throw off rule by strong Eastern empires. When Persian Emperor Artaxerxes III Conquered Egypt again and removed the famous last native Egyptian Pharoah, Nectanebo II, the country would again chafe under this empire until Alexander the great's famous liberation of the country, albeit with the establishment of the Greek Ptolemaic dynasty. If the traditional accounts of Alexander's conquest are authentic, then it seems to me that Egypt would and probably could throw the Persians off again should the Achaemenid empire experience another period of weakness, be it from internal unrest or a defeat from some external empire.
Could such an empire claw its way back to independence and somewhat revive Ancient Egyptian civilization for the Classical Era?