Continuing "Anglo-American Animus"

The British Empire was the United States' first enemy and many in America's founding generation were severe Anglophobiacs. This animus continues for some time in much milder form until the early 20th Century, I remember reading that FDR once told Churchill that Americans had a natural distrust of the British, seeing them as "Imperialists". However by the middle of the century until today, the US and the UK were locked in a "special relationship", but what POD's (probably from the early to mid-19th Century) could perpetuate the "Anglo-American Animus" well into the 20th Century?

Maybe one where the Oregon territorial dispute remains unresolved which leads to President Polk running for a second term in which he goes to war with the British over the territory. The most common one however seems to be British support for the Confederacy during the ACW, but what other scenarios are possible?
 
The British Empire was the United States' first enemy and many in America's founding generation were severe Anglophobiacs.
Don't agree -- Historically pre ARW The Colonies Enemy Was France, and despite their help in the ARW, by the 1790's they were again.

However if the War of 1812 was a little more Vicious, whe could get another generation believing in Peridictious Albion. Then whe have 54-40 or fight, and the ACW.
A little dust-up over Venezuela in the 1890's, and whe enter the 20th Century, with the US v the UK as a stable Mene of world politics.
 
It's true. For about 100 years, one of the major fears of the French state was that the USA would voluntarily rejoin the Empire. Just look at the sheer volume of trade the Americans did with the British.
 
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