So what if to smooth things over even more between the Habsburgs & William the rich (
https://en.wikipedia.org/wiki/William,_Duke_of_Jülich-Cleves-Berg), someone insists that Amalia of Cleves (
https://en.wikipedia.org/wiki/Amalia_of_Cleves) weds Charles V.
I know Charles had a deep love for his deceased Isabella and as such didn't wed again following her death in 1539, and William didn't particularly like the Habsburgs but for the sake of argument it comes up somehow either
Charles (I'll marry your sister, the territories can be considered her dowry, if we have kids they'll inherit the low countries, you won't attack me because I married to your sister)
OR
William (I'll know what your up to because my sister is your wife, increase my influence as I have a sister for an Empress and my other sister has some influence in England, making me more of an international player; it also acknowledges to a degree my family's claims to those territories, I'm cool with the Emperor now)
OR
Mary of Hungary (These 2 guys will be the end of me, I need someone to help mediate relations between the 2, ah! William has a sister ,perfect, sure she a little older kids aren't necessary, afterall our dear sister Isabella married Charles at 23 and our dear sister Eleanor is Queen of France and she married that darn Francis at 32, why not follow those examples no?)
Amalia would've been 26 around 1543 when the treaty was negotiated. I believe Mary of Hungary oversaw it's particulars, but I could be mistaken as the page on the Italian War 1542-1546 (
https://en.wikipedia.org/wiki/Italian_War_of_1542–46#Initial_moves_and_the_Treaty_of_Venlo) implies Charles was campaigning in the region, the marriage could take place in the late winter that year before Charles moved to Speyer to negotiate with the German princes. (Also does anyone know if William's marriage to Maria of Austria, Ferdinand I's (later HRE) daughter was arranged at this time? Can't find particulars on the treaty to that level)
So guys, I'll leave it to you to speculate... Do they have kids, a son, a daughter maybe more? Will Charles give them the low countries? Relations with England? The succession in the Empire (who becomes Emperor, the Burgundian branch or the Austria branch?) With no Low countries to tempt parliament, will they accede to a marriage between Mary I & Philip of Spain? Who does Philip marry instead (sorry I've gotten a bit excited).
Sidenote:
I believe this has bubbled up before (2014 & 2015) but this particular match hasn't been well explored, it's usually more Charles and Anna instead.