Title pretty much says it all. What is the latest date Indians could plausibly wipe out one of the original thirteen colonies?
By wiped out, I mean everyone either killed, captured, or forced flee the bounds of the colony. No time-travelers or space lizards, of course, (since this isn't in the ASB section) just Indians and possibly plausibly available Europeans, with the heavy lifting being done by Indians.
The wipe-out doesn't have to be permanent. If the territory involved gets reoccupied in twenty years it still counts. Reoccupation in ten years should probably be the minimum though.
South Carolina could have been destroyed possibly as late as 1715. The Yamassee War of 1715 came close to achieving that goal. If the British governor had not been able to get the Cherokee involved on their side, the Yamassee and their allies might very well have been successful.
In addition, right around that same time, the Tuscarora War in North Carolina ended, which meant North Carolina could send help to South Carolina.
So how about this scenario. The Tuscarora War begins in 1711 per OTL. The Yamassees and allied Creek tribes begin their war two years earlier, in 1713. Lets assume a Tecumseh-like figure among the Creeks arises who is able to persuade the Cherokee to come in on their side, and also forges an alliance with the Tuscarora. Just to sweeten the deal, the Spanish, who are currently fighting the English in the War of the Spanish Succession, ally with the Yamassee.
Now South Carolina is pressed on three sides. There's no Cherokee help coming, there is no North Carolina help coming. The Indians take Charlestown and massacre the inhabitants in 1714. The only survivors are those who can make it out to a ship in the harbor and get away. Spain sends in some troops to help the Indians keep the English away. In the peace treaty, England agrees to abandon South Carolina and Spain formally sets her northern limit at the line of the Black and Saluda Rivers. The territory between that and North Carolina is to be a buffer zone, controlled by the Indians.
The Spanish govern the new territory much as they do Florida...in other words, not very much. They build a few forts to maintain the border against the English, and a few missions to work to save the souls of the Indians, but not much else. As a result the Yamassee are okay with the arrangement...they have Spanish protection to back them up against the English, with not too much interference in their local affairs. The arrangement lasts until the War of Jenkins' Ear breaks out in 1739, when an expedition led by General James Oglethorpe is sent to reconquer South Carolina for England.
EDIT...upon checking, South Carolina didn't separate from North Carolina until 1729. However, the scenario could be expanded to include the entire Carolina colony. Have the Tecumseh-analog persuade the Northern Tuscarora not to turn on the Southern Tuscarora and defect to the English side...perhaps Chief Blunt, the pro-British chief of the Northern Tuscarora, has a falling out with the Blount Family, his British friends, just before the arrival of the Creek emissary. This, plus Spanish and Yamassee support once Charlestown is taken and destroyed, tips the scales in North Carolina as well. The final peace treaty stipulates that the territory between the Black/Saluda line and Virginia becomes the buffer zone.