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I love the idea of Gran Colombia, and would be immensely curious what could have changed to not only keep it around by have it be a Great Power by the time the Great War breaks out.
The first step I can think of is building the Panama Canal ASAP for trade but beyond that I can't decide much.
So somehow make a Gran Colombia that not only still exists by 1914 but have it on the Great Power level by the time the war breaks out.