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In Decision Points, George W Bush mentions that Cheney was willing to step down as running-mate for W's second term due to the perception that the Vice President was secretly running things/had a tremendous amount of influence. W ultimately opted against.
What if W had accepted the idea and replaced Cheney? Who might he replace him with? Giuliani perhaps? DHS Secretary Ridge? John McCain?
What would be the effect come 2008 when the GOP has an heir apparent?