Answer Depends on Flexibility I have.
Please Note that will keep some of the mindset of Hitler. Jews are evil, Soviets are evil and Germany is to be made a first class power. So this isn't me saying these things are good ideas.
If POD is after invasion of Poland.
1) It's time to fire Goering as Head of the 4 year plan and his role in the economy. It was fine to play political games in peace time but now that there is a real war on need to fight it. So assigned Fritz Todt as Reich Minister for Armaments and Munitions in 1939; Speer is Todt's deputy. End the bureaucratic mess of armaments by making the 3 services answerable to Todt and he absolute control raw materials, workers and factory assignment.
2) The deal with Soviets is a good one so push it to the limits in terms of raw materials.
3) Nothing Massively wrong with invasions of Denmark & Norway or Western Europe as historic. Any changes here I think require foresight so wouldn't make any.
4) After fall of France make a serious pitch at peace with UK. Make clear fate of occupied territories in the west is on the table for talks; IE everything accept Poland is open to talks. Make clear that Germany has no interest in occupation of UK itself. Odds are Churchill wont budge but you can at least make it painful for him politically. Start serious if slow talks with occupied nations for long term peace deals. Will organizing a European Block and some selective annexations. Warsaw Pact 0.1 with common currency perhaps.
5) After giving UK a week to think over the offer in 4 accept two things. First they are going to have be forced out of the war. Second Battle of Britain / Sea Lion aren't the way to do it; as bluff or as real plan. Only place can get at UK interests is Med. So talk to IL DUCE and work out a strategy for kicking the British out of the Med over next year or so. Keep pounding on the UK in the med objectives are Malta, Egypt and Gibraltar. All the while continuing to offer 'reasonable' peace terms, if 2 out of 3 are taken by summer 41 I expect that Churchill is going to start facing real pressure to do a deal.
6) Recalculate Economics program. Much of the pre-war assumptions don't make any sense now, especially with respect to raw materials.
7) Expect that Mussolini will do stupid stuff from time to time so will get sucked into Balkans, etc as historic.
8) If have taken Egypt, etc and UK still hasn't made a deal accept that you are stuck with them at your back and there is nothing to do about it unless willing to change objective to marching East to India. Since even Alexander failed at this turn eyes toward USSR. If UK does bows out go with Madagascar solution for Jews etc, logistics of the movement is UK's problem as part of the peace deal.
9) Accept that USSR is a multiyear campaign and will need to go deep into Russia to make it work. So more trucks, railroad engines, rolling stock and of course engineers are needed.
10) Consider perhaps trying to lure / provoke Soviets into attacking first. Poland is wonderful sack to lure the Soviets into. Logistics all favor the Germans and tactical air power can be used to full effect. If the Soviets attack they are ones trying to cram troops forward and the Germans can kill them with maneuver and airpower. Once Soviet offensive is smashed switch to counter offensive to role the soviets up.
11) Offer Freedom of people in western USSR. Tell them kill the Communists and kill the Jews. Independent nations after the war is won; I am Hitler and an evil SOB so I am lying through my teeth but whatever. Declare great crusade against communism, so recruit troops from occupied nations in west; wouldn't expect much more than historic SS totals but it might generate more if in combination of real effort at peace talks with the occupied nations.
12) Advance into USSR, rip off chunks of territory, organize and repair logistics. Repeat till someone shoots Stalin.
13) Don't declare war on USA. When Japan attacks USA and everyone else in Dec 41 renew offer of peace deal with UK. It can't hurt and if things look bad enough in Europe might even work.
14) Even with the cry being kill the jews in USSR don't set up active death camps, it's a logistical drain on the system. Ghetto's etc are good enough for now.
If POD is 1941.
1) Increase authority of Todt and other economic moves as described above.
2) Think seriously about delaying invasion another month. The invasion of the Balkans put a lot millage on the trucks and tanks of the German army and that needs to be made good still.
3) When attacking Soviets keep in mind that a winter halt line of some type needs to be found. No racing to Moscow to arrive at end of logistical tether just in time for winter to arrive. As above this is a multiyear campaign.
4) As above make campaign kill the Jews and Kill the Communists; freedom for peoples of Western Soviet Union.
5) Logistical problems mean that army is going to strip occupied territories of food so there is going to be famine and even starvation but try to avoid making it needlessly worse.
6) Don't declare war on USA.
Again comments on kill the jews, etc is attempt to keep this in mind set of Hitler, not my own thoughts on the matter.
Michael