With a POD at the time of Champlain (first decade of 17th century), we could have the settlement at Port royal fail, meaning that Acadia would never exist. If what is otl the Canadian maritime provinces was still only inhabited by the mi'kmaq come 1650 or so, puritan settlement of the area would totally be possible (it would probably become a northern extension of new england). Probably, in this scenario, you'd see french Quebec fall to the English much sooner than otl, because an english-controlled maritimes could easily cut Quebec off from France. I'm not sure what you could expect after this point though.