Say Italy was to unified into (almost) one, singular nation state. Thus Columbus would be butterflied away from being born. Say the Portuguese or Spanish inevitably discovered the Americas within 20 years after 1492.
What I'm trying to plan and make the most interesting as possible, would be who eventually discovers and claims which lands.
I'm looking for things like a German/Prussian Mexico, Chinese/Japanese California, French Northeastern-U.S., English Texas, etc. Interesting things like that which would lead to interesting wars and results.
What is vital, due to the much-earlier unification of Italy and Renaissance already in progress (past the POD?), is an Italian Confederacy (from Louisiana to Florida) to continue dominating cash crops and an Italian Brazil to provide Renaissance Italy with its much needed wood.
What are some alternate New World change-of-colonization scenarios