Francis will become Duke d’Orleans here as Orleans would merge with the Crown only if the holder become King or all the male line of the first holder died (and neither case would apply here). Don Carlos is the heir presumptive of Sebastian meaning who if he lived (or left legitimate heirs) and Sebastian died childless he (or his line) will inherit Portugal instead of Cardinal Henry.
This Ferdinand is definitely Ferdinand III of Naples as his cousin was Ferdinand II
EDIT: Charles VIII at the time of his death was likely waiting the right moment for another campaign in Italy (and he also needed money and allies before starting another campaign there)
Ok, edited accordingly with Francis being duke of Orleans and Ferdinand being III.
Charles might be waiting for another moment, but we can agree that regency isn't the best moment to start a war and Queen Mother with unstable position in France itself wouldn't want to damage it any further?
And here...ITALY TREES
MILAN
Maximilian I, duke of Milan (Italian: Massimiliano Sforza, 25 January 1493 – 4 June 1530) m. Bona Sforza d’Aragona (2 February 1494 – 19 November 1557)
1) Isabella of Milan (18 January 1519 – 15 September 1559) married Federico II Gonzaga
2) Francesco II Galeazzo (1 August 1520 – 7 July 1572): Succeeded his father as Duke of Milan
3) Beatrice of Milan (13 July 1522 – 28 May 1575)
4) Anna of Milan (18 October 1523 – 9 September 1596)
5) Catherine of Milan (1 November 1526 – 16 September 1583)
6) Ludovico (born and died 20 September 1527): As a result of a fall from a horse, his mother gave birth prematurely and he died at birth
LORENZO D' URBINO
Lorenzo di Piero de' Medici, duke of Urbino (12 September 1492 – 4 May 1519) m. Anne de La Tour d'Auvergne (1496–1524)
no issue
FERRARA
Ercole II d'Este (5 April 1508 – 3 October 1559) m. Margaret Palaeologa (Italian: Margherita Paleologa; 11 August 1510 in Casale Monferrato – 28 December 1566 in Mantua)
1) Ercole d' Este (March 10, 1533 - February 22, 1550), died 16 years old
2) Lucrezia d' Este, born and died in 1535.
3) Anna d' Este, born and died in 1536.
4) Margaret d' Este (1537-1579)
5) William d'Este, duke of Ferrara (April 24, 1538 - August 14, 1587)
6) Philip d' Este (October 22, 1539 - October 23, 1595).
7) Cardinal Louis d'Este (1540 - February 21, 1565)
NAPLES
Ferdinand III of Naples (15 December 1488 – 20 October 1550) m. a) Germaine of Foix (Catalan: Germana de Foix; French: Germaine de Foix; c. 1488 – 15 October 1536)
b) Anne of Britanny and Touraine (16 November 1531 – 1607)
1a) Frederick, duke of Calabria, who died hours after being born on 3 May 1509.
2a) Isabel of Naples ( Naples , 1518-1565) m. Philip II of Spain (Spanish: Felipe II; 21 May 1527 – 13 September 1598) - see under SPAIN section
3b) Charles IV of Naples (1550–1600)
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