Alfonso of Avila survives his brother, Henry IV of Castile?

In OTL, Alfonso was used as a pawn by the nobles of Castile against his brother Henry IV. When he died from either the plague or being assassinated, they then moved to position Isabella to be Queen instead of Juana, Henry's daughter, leading to the Second War of Castilian Succession. So what if Alfonso doesn't die from either the plague or being assassinated? Would there still be a war between him and Juana? I know Henry had tried to make them become engaged to unite the claims but I don't really see that happening.

Who would be a potential bride for Alfonso XII? Would he be able to reverse the decentralization of his brother as Isabella did in OTL? He died at fourteen so we don't know much about how he would have ruled in any case but I could see him being similar to his elder sister.
 
The Spanish wiki page for him offers more info than the English version obviously

"Estalló entonces la guerra abierta entre los partidarios de Enrique IV y los de Alfonso XII, que instaló su brillante Corte en Arévalo y llegó a reinar de hecho durante los tres años que duró el resto de su vida, envuelto en un lujo y esplendor cultural de que se hizo lengua uno de sus cortesanos, Jorge Manrique, en sus melancólicas Coplas a la muerte de su padre:[4][5]

Pues su hermano el Inocente,
que en su vida subcesor
se llamó,
qué corte tan excelente
tuvo y quánto gran señor
que le siguió!

En la corte de Alfonso XII el Inocente figuraban caballeros tan importantes como Diego Gómez Manrique y su sobrino Jorge, el jurista Nicolás de Guevara y el poeta cancioneril Juan Álvarez Gato o el historiador Diego de Valera, maestresala del rey en 1467, aparte del propio Marqués de Villena; también Rodrigo Alonso Pimentel, cuarto Conde de Benavente, y Pedro de Villandrando Conde de Ribadeo, y Diego de Ribera, ayo del príncipe Alfonso y caballerizo mayor de su corte, o Sancho de Rojas, señor de Cavia y Monzón y alcalde mayor de los hidalgos de Castilla; Martín de Távara; el prior de Osma, jurista y capellán real de don Alfonso XII Francisco Gómez de Miranda y otros. Por cierto que en su capilla figuraban cantores tan destacados como Diego Rangel o Cristóbal de Morales. Don Diego Gómez Manrique organizó festejos y compuso momos teatrales para celebrar el cumpleaños real en los que las damas de la Corte hacían el papel de hadas. Otro producto del mecenazgo real fue un espejo de príncipes redactado para el uso de Alfonso XII: la Exhortación o información de buena e sana doctrina (1467) escrita por el humanista Pedro de Chinchilla a instancias del ya citado cuarto Conde de Benavente."
 
I know that in OTL the funding for Columbus came from aragon. Maybe in a divided Spain scenario like this, Isabella could convince Ferdinand to fund her brothers support for Colombus for a division of the profits from the voyage, setting up for Aragon to get some territorial claims in the new world.
 
I asked this question in an earlier thread and I think the consensus was that there could have been a double wedding between Castille and Aragon. Isabella and Ferdinand would marry as per OTL, and Alfonso XII would marry Ferdinand's sister Joanna, who IOTL married King Ferdinand I of Naples.
 
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